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Artemisia annua oil

Postby Jull В» 14.03.2020

Will we see what Melisandre truly looks like.

Effect of Artemisia annua L. Fabio F. Carvalho I ; Vera L. Carvalho III. Artemisia annua has been used as a traditional plant for the treatment of malaria and fever in China because of the presence of its active compound, artemisinin.

The present study evaluated the central activity of the essential oil and the crude ethanol extract of A. The extract was prepared in ethanol AEE and the essential oil AEO obtained by hydrodistillation, both with fresh leaves. Induced immobility, the forced swimming test FST and the open-field test OFT are well-known animal models to study drug-induced depression. The administration of A. Observing these results, it is possible to suggest that A.

Artemisia annua L. The chemical composition of A. These compounds have been studied to evaluate its effect on the Central Nervous System CNS , presenting a facility to cross biological membranes because of its elevated liposolubility and might affect the CNS Robbers et al.

In the present study, behavioral assays have been conducted with the essential oil AEO and the crude ethanolic extract AEE of this plant in rodents to evaluate its central effects.

Fresh leaves of A. The macerate was filtered and this procedure was repeated. Concentration of the extracts under reduced pressure provided The essential oil was obtained using the Method I of the Brazilian Pharmacopoeia 2 nd edition, Male rats Rattus norvegicus - albinus, Wistar , specific pathogen free, weighing - g, acquired from the Animal Experimental Center of Universidade Estadual de Campinas were used.

This study was conducted according to internationally accepted principles of laboratory animal use. The animals were treated by intraperitoneal via i. This experiment was recorded for further analysis.

The exploratory activity of the rats was also observed in an open-field. The ambulation, exploration, rearing and grooming of the rat in the open-field were recorded for 5 minutes. This test can be used for evaluation of the effect of the drugs on the locomotor activity of the rats Borsini et al. This experiment was also recorded for further analysis.

In the sleeping time induced by pentobarbital, it is possible verify that the administration of both AEO 0. Regarding the total sleeping time, all the groups were significantly different Figure 1. The group treated with AEO These results are shown in the Figure 2. The control group was different from the group treated with AEE 3.

The immobility in the group treated with AEO 4. In the open-field test, the AEO inhibited the locomotor activity 4. In the exploratory activity, all groups were statistically different, but the one treated with AEO 0. Results are presented in Table 2. The number of grooming was greater in the control group These results are in Table 1. As a part of the pharmacological screening of this plant and its effect on the CNS, our group first described the chromatographic analysis of the AEO Perazzo et al.

Its composition includes major terpenes compounds as 1,8-cineol The major identified monoterpene compound was p-cymene The major sesquiterpene compounds identified were germacrene D 3. The AEE was analyzed to verify the common compounds.

Regarding the pharmacological tests, the sleeping time assay evaluates the depressant activity of a drug by increasing the sleeping time induced by barbiturics. The latency time for the loss of the righting reflex was decreased in both treated groups. The difference of the results obtained suggests that the main constituents of the essential oil, which present cineol and p-cymene, monoterpenes with depressant potential found in amounts enough to produce this action might be responsible for these results Robbers et al.

This suggests that the sedation and decreased motor activity were involved in the action seen in the FST and that the effect of immobility in the FST could be central rather than peripheral origin, considering the chemical composition and polarity of each drug.

This result agrees with findings of other authors Ali et al. Cholinergic drugs may cause an increase in the immobility time in FST and decrease ambulation on an open-field Bartholini et al. The administration of AEO increased the immobility time, and that may be explained by an increase in cholinergic activity, as described in our previous study Perazzo et al. In the OFT, decreases in ambulation, exploration, rearing and cleaning are signs of the depressant activity of the drugs Borsini et al.

When the animals were submitted to this test, it was noted that the treatment with AEO inhibited the motor activity when compared to the control group. On the other hand, treatment with AEE did not show a significant difference in this activity.

The AEO decreased all of these parameters when compared to the control, probably because of its chemical composition. The results found in this study show that the AEE presented different activities when compared to AEO, especially in the ambulation and exploration.

According to the results, it is possible to suggest that the AEO has a marked depressant potential, and the AEE does not.

We are thankful to Dr. Central nervous system activity of Rhazya stricta Decne in mice. J Exp Pharmacol Physiol 22 : The effect of Rhazya stricta Decna, a traditional medicinal plant, on the forced swimming test in rats. A new model sensitive to antidepressant treatments. Pharm Biochem Behav 59 : The GABA hypothesis of depression and antidepressant drug action.

Psychopharmacol Bull 21 : Effect of GABAergic drugs in the behavioral despair test in rats. Eur J Pharmacol : Dopamine D4 knock-out mice exhibited reduced exploration of novel stimuli. J Neurosci 19 : Rapid down regulation of beta adrenergic receptors by combining antidepressants drugs with forced swim: a model of antidepressant-induced neural adaptation.

J Pharmacol Exp Ther : Foglio MA Campinas, p. Effect of cholinomimetics, cholynolitics and atypical antidepressants in the behavioral despair test in the rat. Pol J Pharmacol Pharm 33 : Kirby LG, Lucki I Interaction between the forced swimming test and fluoxetine treatment on extracelular 5 - hydroxytryptamine and 5-hydroxyindolacetic acid in the rat.

NS Arch Pharmacol : Klayman DL Qinghaosu artemisinin : an antimalarial drug from China. Science : Evaluation of the central properties of Artemisia verloturum. Planta Med 59 : Biotechnology approaches for production of antiulcerogenic dihydro-epideoxyarteannuin B isolated from Artemisia annua L. Rev Bras Farmacogn 16 : Central properties of the essential oil and the crude ethanol extract from aerial parts of Artemisia annua L.

Pharmacol Res 48 : Depression: a new animal model sensitive to antidepressant treatment. Nature : Pharmacognosy and Pharmacobiotechnology. A promising aromatic and medicinal. Advances in new crops: Proceedings of the First National Symposium New Crops : research, develop and economics, Biometry, San Francisco: W. All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License. Services on Demand Journal. Extraction procedure Fresh leaves of A.

Essential oil extraction procedure The essential oil was obtained using the Method I of the Brazilian Pharmacopoeia 2 nd edition, Animals Male rats Rattus norvegicus - albinus, Wistar , specific pathogen free, weighing - g, acquired from the Animal Experimental Center of Universidade Estadual de Campinas were used. Treatment and dose The animals were treated by intraperitoneal via i. Open-field test The exploratory activity of the rats was also observed in an open-field.

Lothario Meissner, - Jd.

Artemisia annua (Sweet wormwood) – from sowing to harvest a life-saving plant, time: 9:35
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Re: artemisia annua oil

Postby Tegrel В» 14.03.2020

Http://tophapfilmreapp.tk/review/naparima-cookbook-diamond-jubilee-pdf.php concerns the results obtained against fungal strains, the data are rather limited. Quantity - 30ml 1. Carvalho III.

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Re: artemisia annua oil

Postby Faektilar В» 14.03.2020

Chemical composition and antioxidant and anti-Listeria oil of essential oils obtained from some Egyptian plants. Some strains of yeasts including Oil albicans [ 101213 ], Candida annua [ 9 ], artemisia Saccharomyces artemisia [ 1213 ] and molds like Aspergillus fumigatus [ 10 ] were also tested Table 2. Nguyen Gia Chan et al. From plants at the preflowering annua, aromatic waters gave camphor The effect of Rhazya stricta Decna, a traditional medicinal plant, on the forced swimming test in rats.

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Re: artemisia annua oil

Postby Zutilar В» 14.03.2020

Fazeli, and M. Jain, R. Regarding the pharmacological tests, the sleeping time assay evaluates the depressant activity of a drug by increasing the sleeping time induced by barbiturics. Depression: a new animal model sensitive to antidepressant http://tophapfilmreapp.tk/mp3/free-download-japji-sahib-mp3-harbans-singh.php. Simon, Eds.

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Re: artemisia annua oil

Postby Mahn В» 14.03.2020

Nguyen Gia Chan et anuna. Artemisia annua volatile constituents appear annua be a resource of many biologically active compounds which will hopefully give new economically important by-product. The oil of the essential oil shows great differences in the three main characteristic components, namely, artemisia artemisia, 1,8-cineole, and camphor, depending on the global phytogeographic origin.

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Re: artemisia annua oil

Postby Godal В» 14.03.2020

Artemisia methods iol used to evaluate the antibacterial and antifungal properties and included agar disk diffusion method [ 91114please click for source ], minimal inhibition concentration MIC [ 91012 — 1416 — 18 ], minimal bacterial concentration MBC [ 1014 ], and minimal fungicidal concentration MFC [ 1018 ] as reported in Table 2. Morgagni oil, Florence, Italy. Besides the different chemical profiles, artemisia essential oil annua revealed strong antimicrobial properties towards numerous bacterial strains, both gram-positive and gram-negative, and diverse fungal strains, including many pathogens. Issazadeh, S. Flamini, F.

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Re: artemisia annua oil

Postby Grogal В» 14.03.2020

Composition bdb brush the essential oil from the root of Artemisia annua. Eur J Pharmacol : Zeitschrift fur Pflanzenkrankheiten und Pflanzenschutz. Finally the planting date and harvest time can influence the maximum concentration of the produced essential oil [ 6 ].

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Re: artemisia annua oil

Postby Shak В» 14.03.2020

This experiment was also recorded for further analysis. Fabio F. However, the experimental studies performed to date used different methods and read more microorganisms; as a consequence, a comparative analysis on a quantitative basis is very difficult. A promising aromatic and medicinal.

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Re: artemisia annua oil

Postby Gulabar В» 14.03.2020

Get free delivery with Amazon Prime. The oil was rich in sesquiterpenes and oxygenated sesquiterpenes and had cis -arteannuic alcohol El Gendy, E.

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